British number three Heather Watson lost to Greece's Maria Sakkari in the first round of the Nature Valley Open in a rainy Nottingham.
The 27-year-old, who made the quarter-finals at Surbiton last week, was beaten 6-4 6-3 by Sakkari, who is ranked 82 places higher in the world.
Fellow Briton Harriet Dart beat Vera Lapko in three sets to book a last-16 match with Australian Ajla Tomljanovic.
Compatriot Katie Swan lost to American Bernarda Pera 7-6 (7-5) 6-1.
For a second successive day, no play was possible on the grass courts at the Nottingham Tennis Centre with action moving indoors and on to a hard surface.
The all-British match-up between former top-50 player Dan Evans and Jack Draper in the men's tournament has been postponed until Thursday.
Elsewhere Canada's 2016 Wimbledon runner-up Milos Raonic overcame France's Jo Wilfried-Tsonga 6-4 6-7 (5-7) 7-6 (7-1) in a match that stretched to two hours and 29 minutes in the ATP event in Stuttgart.