British number three Kyle Edmund is out of the Qatar Open after losing 6-3 6-2 to world number six Tomas Berdych.
Despite the defeat, Edmund, currently ranked 102nd, will better his career-high ranking of 99 when the new standings are released next week.
Berdych will play Novak Djokovic - against whom he has won two of 23 meetings - in the last four.
World number five Rafael Nadal also advanced with a 6-3 5-7 6-4 win over Russia's Andrey Kuznetsov.
Nadal was made to work for his victory by the world number 79, but prevailed in just over two hours.
He will next face Ukrainian world number 94 Illya Marchenko, who upset Frenchman Jeremy Chardy 6-3 7-6 (3).