Will Collier and Nick Evans add to Harlequins injury list
Harlequins prop Will Collier will be out for two months after having an operation on a broken ankle.
The 25-year-old, who came through the club's academy and made his first-team debut in 2011, sustained the injury in the 29-26 win over Sale on 7 January.
Meanwhile, fly-half Nick Evans will be out for a month with a fractured wrist suffered in the same match.
The pair add to Quins' injury list, which includes England internationals Joe Marler and Chris Robshaw.
Loosehead Mark Lambert remains out until mid-February, while centre George Lowe (back) is sidelined for another six weeks.
Sam Twomey (foot) and Harry Sloan are long-term absentees.
Australia lock James Horwill is expected to return from injury for the European Challenge Cup game against Stade Francais on 22 January.