Tamara Taylor will earn her 90th England cap on Saturday after being named in the starting XV to face Wales at Twickenham Stoop (18:05 GMT).
Coach Scott Bemand keeps the same squad who beat defending Six Nations champions Ireland as England look to make it four wins from four games.
Harriet Millar-Mills drops to the bench to make way for second row Taylor.
"The team has improved with each win and we look forward to having the support of a home crowd," Bemand said.
England kicked off their 2016 Six Nations campaign with a 32-0 win over Scotland.
They followed that with a 33-24 victory over Italy before beating Ireland 13-9 at Twickenham.
England: Katie Mason, Lydia Thompson, Lauren Cattell, Ceri Large, Lotte Clapp, Amber Reed, La Toya Mason, Sarah Hunter, Izzy Noel-Smith, Abbie Scott, Tamara Taylor, Emily Braund, Vickii Cornborough, Emma Croker and Rochelle Clark.
Replacements: Amy Cokayne, Heather Kerr, Bianca Dawson, Harriet Millar-Mills, Poppy Leitch, Bianca Blackburn, Ruth Laybourn, Leanne Riley.