Pool four leaders Wasps maintained their unbeaten start to the Challenge Cup with victory over Grenoble.
Wasps led 14-0 at the break after tries from Will Helu and Guy Thompson with Joe Carlisle kicking two conversions.
Thompson got his second, which Carlisle converted, before Charlie Hayter sealed the four-try bonus point for Wasps.
Olly Barkley converted Cedric Beal's try for the hosts but scores for Hayter, Jack Moates and Josh Bassett, which Tommy Bell kicked sealed it.
Grenoble: Caminati; Kilioni, Jaouher, Messina, Nicolas; Gengenbacher, Bezy; David, Campo, Edwards, Rey, Hulme, Beal, Vanderglas, Alexandre.
Replacements: Hegarty, Fabro, Choirat, Faure, Barkley, O'Leary, Hart, Bernard.
London Wasps: Daly; Bassett, C Bell, Hayter, Helu; Carlisle, Simpson; Mullan, Festuccia, Cooper-Woolley, Launchbury, Palmer, Haskell, Thompson, Jones.
Replacements: Lindsay, Vea, Swainston, Myall, Jackson, Moates, T Bell, Jacobs