England centre Joel Tomkins is likely to miss the start of the Six Nations in February after injuring his knee against New Zealand last weekend.
The 26-year-old Saracens back, who won his first cap against Australia earlier this month, left the field 77 minutes into the 30-22 loss to the All Blacks.
Sarries director of rugby Mark McCall said: "Joel will be out for quite some time, probably three months."
England are already without Leicester lock Geoff Parling for three months.
The 30-year-old had shoulder surgery after he too was injured against New Zealand.
England meet France in Paris on February 1 in their opening match before a trip to Murrayfield to face Scotland the following weekend.