Wales have named the 35 players who will travel to Spala in Poland for their second World Cup training camp.
As expected Jonathan Thomas, Andy Powell and Richie Rees will not be among the travelling party.
Ken Owens, Lou Reed, Andrew Bishop, John Yapp and Scott Andrews will also be left behind.
But Stephen Jones, who missed the first training camp for the birth of his first child is among the players travelling.
Gareth Delve and Dwayne Peel are unavailable while Richard Hibbard and Jason Tovey will remain in Wales because of injuries.
Head coach Warren Gatland selected an initial 45-man training squad has trimmed the numbers down to 35 as he takes the players for a second week of intense training in Poland.
"The nature of the training regime next week meant we were always going to take a smaller group of players, because of the strong rugby element involved," Gatland said.
"The players on the camp have an opportunity to work hard and impress, but it will not be a case of out of sight out of mind for those players who remain at home."
Gatland was keen to emphasise the World Cup dream is not over for the players who would not be travelling to Poland.
"The door is still very much open for those players who are not making this trip," added Gatland.
"This camp will have a strong focus on rugby whilst retaining the skills and conditioning elements of our first visit to Spala.
"It will give us further opportunity to see more of some players in particular in and intense rugby environment, with the likes of Ryan Bevington, Lloyd Burns, Justin Tipuric and Scott Williams all gaining an extra opportunity to show us their worth."
Jonathan Thomas' omission comes after the versatile Ospreys forward played in all but one of the Six Nations matches last season, and played the full 80 minutes in the autumn internationals against Australia, South Africa and Fiji.
The 28-year-old, who has won 66 caps, was a stalwart of the 2008 Grand Slam team.
Rees, 28, was suspended for the whole Six Nations campaign, but the Cardiff Blues scrum-half started two games in the 2010 tournament.
Powell has not featured since starting against England in the 19-26 defeat to England in last season's Six Nations opener.
Of the other three to be omitted, only centre Andrew Bishop has been capped.
Wales are carrying a number of injured players in the training squad, with Leigh Halfpenny's ankle injury of particular concern for Gatland.
But prop Gethin Jenkins, who missed the entire 2011 Six Nations campaign after having foot surgery, is approaching full fitness and hoping to return for the three warm-up games against England (twice) and Argentina in August.
"It's important for our final preparation, to get a place in that squad and to get a place on the plane, to do well in Poland," Jenkins said.
"We want to be at our fittest and most powerful, but we also know that unless we can play rugby as well it won't matter a jot.
"The camp has been tough mentally and physically, but the next challenge will then be to perform on the pitch.
"We will be strong and fit, but we need to convert that into performing in games.
"There is only so much you can learn about a rugby player from a fitness test and these games against England and Argentina will be the opportunity for the coaches to assess the players in a match.
"Those Tests will be the acid tests. Hopefully, if I get my chance, it will go well and I can go to the World Cup, but I'm not taking anything for granted."
After the three warm-up Tests, Gatland must name his 30-man squad for September's World Cup in New Zealand by 22 August.