Following a recent run that included a win at leaders Ealing, Jersey face Taunton - one of only three teams to have beaten the islanders this season.
Coach Ben Harvey can choose from almost a full squad, with the exception of Nathan Hannay and Dave Docherty.
In the back row, Charlie Clyde-Smith makes a start, replacing the experienced Graham Bell.
Second-placed Jersey will be hoping for a bonus point win, and then hope Old Albanians beat leaders Ealing.
This would reduce the gap between Jersey and the league leaders to just three points.
Harvey said: "I'm pretty confident that Old Albanians will do a good job, whether they win the game or not I don't know.
"Ealing have been very lucky with injuries this year, they've pretty much had the same team all season."
Meanwhile, Harvey is confident his side are well prepared for their own match.
"I've mixed it up a bit, kept people fresh and gave those that needed a kick a bit of a kick.
"Hopefully we have prepared accordingly."