Winger Darcy Graham will miss Scotland's Six Nations opener against Ireland next Saturday due to a knee injury, while Duncan Weir is called up in place of absent Finn Russell.
England's Ollie Thorley says there is "no difference" in the camp following Saracens' salary cap breaches.
Jacques Nienaber is confirmed as South Africa's head coach as World Cup-winning boss Rassie Erasmus returns to the role of director of rugby.
Wing Owen Lane is released from Wales' Six Nations squad following a "significant hamstring injury" sustained in training.
Chris Jones and Ugo Monye are back at the Six Nations launch to chat to Jonny Sexton, Stuart Hogg, Owen Farrell, Alun Wyn Jones and all of their coaches.
Six Nations
Premiership
Pro14
Premier 15s
Owen Farrell says Saracens' relegation for salary cap breaches is "disappointing for everyone involved" but he backs the club to "come back stronger".
English champions Saracens will be relegated from the Premiership at the end of the season. BBC rugby union correspondent Chris Jones explains why.
Saracens' relegation is as momentous to rugby union as the same happening to Sir Alex Ferguson's Manchester United would have been to football, says Tom Fordyce.
Danny and Chris Ashton are back with Ugo as they give their thoughts on the Saracens salary cap scandal.
Tom Curry talks to BBC Sport about being trolled by Faf de Klerk, visiting cat cafes in Japan - and a disastrous trial at Manchester City.
How former England coach Stuart Lancaster rebuilt his reputation in Dublin and helped develop one of Europe's most dominant teams.
From winning Love Island to helping make Irish rugby history, 2019 was a whirlwind year for Greg O'Shea, who now has his sights set on the Olympic Games.
After making 34 appearances in eight tournaments between 2010 and 2017, Sam Warburton thought his Six Nations days were over. He was wrong.
Sam Warburton or David Pocock? Owen Farrell or Ma'a Nonu? Here's who the Rugby Union Weekly podcast and BBC Sport users picked in their team of the decade
Find ways to get active
Trash talk, haka challenges, new stars burning bright and nation-uniting triumphs - how much do you remember of these iconic Rugby World Cup moments?
Get latest scores and headlines sent straight to your phone, sign-up to our newsletter and learn where to find us on online.
How to get into rugby union - get into the social team game that brings people together
Enjoy the best debate, analysis and interviews with BBC 5 live and World Service plus our rugby union commentary listings.
