Winger Darcy Graham will miss Scotland's Six Nations opener against Ireland next Saturday due to a knee injury, while Duncan Weir is called up in place of absent Finn Russell.
England's Ollie Thorley says there is "no difference" in the camp following Saracens' salary cap breaches.
Jacques Nienaber is confirmed as South Africa's head coach as World Cup-winning boss Rassie Erasmus returns to the role of director of rugby.
Wing Owen Lane is released from Wales' Six Nations squad following a "significant hamstring injury" sustained in training.
Audio & Video
Owen Farrell says Saracens' relegation for salary cap breaches is "disappointing for everyone involved" but he backs the club to "come back stronger".
English champions Saracens will be relegated from the Premiership at the end of the season. BBC rugby union correspondent Chris Jones explains why.
Saracens' relegation is as momentous to rugby union as the same happening to Sir Alex Ferguson's Manchester United would have been to football, says Tom Fordyce.
Tom Curry talks to BBC Sport about being trolled by Faf de Klerk, visiting cat cafes in Japan - and a disastrous trial at Manchester City.
From winning Love Island to helping make Irish rugby history, 2019 was a whirlwind year for Greg O'Shea, who now has his sights set on the Olympic Games.
Sam Warburton or David Pocock? Owen Farrell or Ma'a Nonu? Here's who the Rugby Union Weekly podcast and BBC Sport users picked in their team of the decade
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