The Tandragee 100 will return to the road racing calendar on 7 May this year after not taking place in 2010.
Several changes have been made to the circuit where two riders were killed in accidents in recent years.
Ardglass rider John Donnan was killed at the meeting in 2007 and Dubliner Martin Finnegan lost his life in a crash the following year.
The paddock area has been moved and the chicane where Donnan was killed has been removed, making the course faster.
"We want to move safety of motorcycling forward," said clerk of the course RJ Woolsey.
"It has been agreed with various committees of the Motorcycling Union of Ireland that the chicane could be lifted and that we could try it this year as a smooth run.
"Safety is the main thing in trying to keep it going."
The Tandragee races will be staged a week after the season opens with the Cookstown event on 30 April.