Scotland head coach Bryan Easson has made three changes from last weekend's 41-20 defeat against Italy.
Loosehead prop Christine Belisle, scrum-half Jenny Maxwell and outside centre Hannah Smith come in, with vice-captain Lisa Thomson moving back to inside centre.
Centre Hannah Jones will captain Wales in their Women's Six Nations fifth-place play-off against Scotland.
GB Sevens hopeful Jones wears the armband in place of Siwan Lillicrap, who is ruled out with an ankle injury.
Scrum-half Megan Davies and hooker Robyn Lock make their first Six Nations starts.
Head coach Warren Abrahams makes nine personnel changes as Wales look to finish strongly after heavy defeats against Ireland and away in France.
Wales: Joyce; Neumann, Rowland, H Jones (capt), Lewis; Wilkins, M Davies; Thomas, Lock, Donna, John, TW Davies, Johnes, Dainton, Evans.
Replacements: K Jones, Jenkins, Hale, Crabb, Powell-Hughes, Fleming, Knight, Webb.
Six stars to watch on the final weekend
Video content
Video caption: Women's Six Nations: Six superstars to watch on the final weekendWomen's Six Nations: Six superstars to watch on the final weekend
Watch the best moments from this year's tournament...
Video content
Video caption: Women's Six Nations: 'Brilliant' Breach's solo try as England thrash ScotlandWomen's Six Nations: 'Brilliant' Breach's solo try as England thrash Scotland
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Video caption: Women's Six Nations 2021: Boujard scores first half hat-trick for France against WalesWomen's Six Nations 2021: Boujard scores first half hat-trick for France against Wales
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Video caption: Women's Six Nations: Watch Dow's try as England thrash ItalyWomen's Six Nations: Watch Dow's try as England thrash Italy
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Video caption: Women's Six Nations: Parsons and Considine score brace as Ireland beat WalesWomen's Six Nations: Parsons and Considine score brace as Ireland beat Wales
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Video caption: Women's Six Nations: Watch best tries as France thrash IrelandWomen's Six Nations: Watch best tries as France thrash Ireland
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Video caption: Women's Six Nations: Furlan scores hat-trick as Italy beat ScotlandWomen's Six Nations: Furlan scores hat-trick as Italy beat Scotland
How can I watch the Women's Six Nations finals weekend?
All times are BST and subject to change
BBC iPlayer
LIve coverage from all three games in the Women's Six Nations finals weekend will be available across the BBC.
You will also be catch up on all the action on BBC iPlayer for 30 days after the event too.
Full coverage details
1150-1400: Ireland v Italy - third-placed play-off - BBC iPlayer and the BBC Sport website & app
1330-1615: England v France - final - BBC Two, BBC iPlayer and the BBC Sport website & app
1650-1900: Scotland v Wales - fifth-placed play-off - BBC iPlayer and the BBC Sport website & app
Live Reporting
All times stated are UK
Video caption: Women's Six Nations: Six superstars to watch on the final weekendWomen's Six Nations: Six superstars to watch on the final weekend Video caption: Women's Six Nations: 'Brilliant' Breach's solo try as England thrash ScotlandWomen's Six Nations: 'Brilliant' Breach's solo try as England thrash Scotland Video caption: Women's Six Nations 2021: Boujard scores first half hat-trick for France against WalesWomen's Six Nations 2021: Boujard scores first half hat-trick for France against Wales Video caption: Women's Six Nations: Watch Dow's try as England thrash ItalyWomen's Six Nations: Watch Dow's try as England thrash Italy Video caption: Women's Six Nations: Parsons and Considine score brace as Ireland beat WalesWomen's Six Nations: Parsons and Considine score brace as Ireland beat Wales Video caption: Women's Six Nations: Watch best tries as France thrash IrelandWomen's Six Nations: Watch best tries as France thrash Ireland Video caption: Women's Six Nations: Furlan scores hat-trick as Italy beat ScotlandWomen's Six Nations: Furlan scores hat-trick as Italy beat Scotland 
Latest PostTeam news
Scotland v Wales
Scotland head coach Bryan Easson has made three changes from last weekend's 41-20 defeat against Italy.
Loosehead prop Christine Belisle, scrum-half Jenny Maxwell and outside centre Hannah Smith come in, with vice-captain Lisa Thomson moving back to inside centre.
Scotland: Rollie, Musgrove, Smith, Thomson, Gaffney; Nelson, Maxwell; Belisle, Skeldon, Kennedy, Wassell, McMillan, Gallagher, McLachlan, Cattigan.
Replacements: Rettie, Bartlett, Cockburn, Howat, McDonald, Law, Wills, Shankland.
Centre Hannah Jones will captain Wales in their Women's Six Nations fifth-place play-off against Scotland.
GB Sevens hopeful Jones wears the armband in place of Siwan Lillicrap, who is ruled out with an ankle injury.
Scrum-half Megan Davies and hooker Robyn Lock make their first Six Nations starts.
Head coach Warren Abrahams makes nine personnel changes as Wales look to finish strongly after heavy defeats against Ireland and away in France.
Wales: Joyce; Neumann, Rowland, H Jones (capt), Lewis; Wilkins, M Davies; Thomas, Lock, Donna, John, TW Davies, Johnes, Dainton, Evans.
Replacements: K Jones, Jenkins, Hale, Crabb, Powell-Hughes, Fleming, Knight, Webb.
Six stars to watch on the final weekend
Video content
Watch the best moments from this year's tournament...
Video content
Video content
Video content
Video content
Video content
Video content
How can I watch the Women's Six Nations finals weekend?
All times are BST and subject to change
BBC iPlayer
LIve coverage from all three games in the Women's Six Nations finals weekend will be available across the BBC.
You will also be catch up on all the action on BBC iPlayer for 30 days after the event too.
Full coverage details
1150-1400: Ireland v Italy - third-placed play-off - BBC iPlayer and the BBC Sport website & app
1330-1615: England v France - final - BBC Two, BBC iPlayer and the BBC Sport website & app
1650-1900: Scotland v Wales - fifth-placed play-off - BBC iPlayer and the BBC Sport website & app