We'll have all the team news for you at 12:30, but here's an early glimpse at who could be in or out for both sides.
Everton are without Andre Gomes, who has been handed a retrospective three-match ban for a challenge on Aleksandr Mitrovic in the defeat at Fulham.
Tom Davies and Morgan Schneiderlin are vying to replace him, while Yerry Mina is still sidelined through injury.
Manchester United may rotate their squad following the midweek Champions League exit, with Ander Herrera back in training after a thigh injury.
Nemanja Matic and Alexis Sanchez are available but Luke Shaw is suspended.