Tiger Woods was a shadow of his former self as he missed only his third cut in a major as a professional with a second-round 73 in the US PGA.
The former world number one ended 10 over par to miss the cut by a distance after a day of struggles in Atlanta.
Americans Jason Dufner (65) and Keegan Bradley (64) lead by one at five under from Jim Furyk, DA Points, Scott Verplank, John Senden and Brandt Jobe.
Rory McIlroy defied Thursday's wrist injury to card 73 to end three over.
Overnight leader Steve Stricker slumped to a 74 after his stunning opening 63 to slide back to three under, while England's Lee Westwood (68) was the leading Briton at one under with countrymen Simon Dyson (72) and Ross Fisher (69) level.
Woods amassed a seven-over 77 on Thursday, equalling his second-worst round in a major, and was left needing a score in the mid to high 60s on Friday to have a chance of making the top 70 players and those tied for 70th going into the weekend.
But the 35-year-old cut a forlon figure as he fought with his swing, catching a host of bunkers and struggling with his distance control.
He dropped shots at the fifth and seventh before showing glimmers of hope with back-to-back birdies at eight and nine.
But a two-hole aberration after the turn sealed his fate. He made a double bogey on the 11th after splashing from a bunker through the green and into the water, and then hooked into trees twice on the long 12th to notch another double bogey.
With the chance of making the cut virtually gone, Woods rallied towards the end of his round and picked up shots at the 13th and 15th but found the water again on the 18th to miss the cut by six shots.
The American, now ranked 30th after a four-month injury lay-off, had previously only missed the cut twice in 56 majors as professional, the 2009 Open and 2006 US Open. He has only missed four other cuts as a pro when he has completed 36 holes.
"It's frustration and disappointment that I'm not contending in the tournament," said the 14-time major champion, who has not won any title since his infamous sex scandal broke in November of 2009.
"It's a step back in the sense I didn't make the cut but a giant leap forward in the sense that I played two straight weeks healthy.
"Today I hit the ball a lot better and putted well but I never got to the green soon enough.
"I showed signs I can hit the ball exactly how I know I can, I just didn't do it enough times."
Having failed to qualify for the PGA Tour's end-of-season Fed Ex Cup play-offs, Woods said he will not play again until November and will spend the time working on his game with coach Sean Foley.
Northern Ireland's US Open champion McIlroy was diagnosed with a strained tendon in his right wrist after hitting a tree root in his first round but reappeared with further heavy strapping and carded a round of three birdies, three bogeys and a triple-bogey on the 17th.
"It was probably tougher mentally more than anything else, trying to get it out of your mind," said McIlroy.
Australian Adam Scott, who won the WGC event last week with Woods's former caddie Steve Williams, enjoyed a share of the lead at five under but dumped his second into the water on 18 and dropped back to two under after a 69.
World number one Luke Donald shot 71 to finish one over alongside four-time major champion Phil Mickelson, who also found water on the last to end with a 70.
Defending champion Martin Kaymer, the world number three, carded rounds of 72, 73 to miss the five-over cut alongside Justin Rose and Australian Jason Day. Ernie Els, Martin Laird, Graeme McDowell and Darren Clarke were also among those to miss the cut.