Tyrone will play Donegal in their Division One North Football League opener with Down facing a trip to Mayo and Antrim hurlers at home to Clare.
With the leagues starting with hurling fixtures, Antrim will host Clare at Corrigan Park on Saturday 8 May.
The football action begins on 15 May with Tyrone meeting Donegal at Omagh and Mayo facing Down in their Division Two opener at Castlebar.
The next day, Monaghan will face Armagh in Division One North at Enniskillen.
Monaghan, Dublin, Down and Cork will all be denied home advantage for any of their round-robin games during the regionalised Football League after breaching the GAA's Covid-19 protocols by holding an unauthorised training session.
Managers banned after Covid protocols breaches
Both the Dublin and Monaghan county boards imposed 12-week suspensions on football managers Dessie Farrell and Seamus McEnaney following their squads' transgressions.
The GAA handed a 12-week ban to Cork boss Ronan McCarthy with Down manager Paddy Tally getting an eight-week ban.
Dublin will be forced to travel to Thurles to take on Kerry in their Division One South game on 23 May with Down having to play their 'home' Division Two North contest with Meath at the Armagh Athletic Grounds on the same day.
Last year's surprise Ulster football champions Cavan will open their Division Three North campaign with a derby game in Enniskillen against Fermanagh on Saturday, 15 May with Derry facing Longford away on the same day also in Division Three North.
Also on 15 May, new Antrim football boss Enda McGinley will have his first competitive game in charge in Dundalk against a Louth team now guided by his former Tyrone manager Mickey Harte.
The last meeting between Tyrone and Donegal saw Declan Bonner's side earn a 1-13 to 1-11 Ulster Championship win at Ballybofey in November which came a couple of weeks after Donegal also clinched a four-point win in the Division One League contest between the counties at MacCumhaill Park.
The second weekend of the football league will see Donegal hosting Monaghan and Armagh welcoming Tyrone on Saturday, 22 May with Derry facing Fermanagh and Cavan playing neighbours Longford on the same day in Division Three North.
The final round of Division One North games will take place a week later with Armagh hosting Donegal and Tyrone playing Monaghan at Healy Park.
Other 29 May contests include both Division Three North games as Cavan meet Derry and Fermanagh have home advantage against Longford.
Down's final Division Two North game will be against Westmeath in Mulligar on 30 May - with Antrim having their second successive Corrigan Park contest against Leitrim a week after their meeting with Sligo.
After their Division One B Hurling League opener against Clare on 8 May, Darren Gleeson's Saffrons will face a daunting trip to Nowlan Park to play Kilkenny eight days later.
The Saffrons will then meet Dublin at Parnell Park on 22 May in a dress-rehearsal for their Leinster Championship opener before having Corrigan Park contests against Wexford and Laois on 5 and 12 June.
Antrim hurlers secured a return to Division One by beating Kerry in last October's Division Two A decider and Gleeson's men later ensured a spot in this year's Leinster Championship and Liam McCarthy Cup campaigns by again overcoming the Kingdom in the Joe McDonagh Cup Final at Croke Park.