Dunfermline Athletic's Scottish Championship match with Dundee on Tuesday has been postponed after a Covid-19 case led to Friday's derby with Raith Rovers being called off.
The club informed the SPFL on Wednesday that they "have insufficient players to fulfil" the match with Rovers due to members of their squad self-isolating.
Dunfermline say the SPFL have confirmed Dundee's trip to Fife is also off.
The SPFL has launched an investigation into the circumstances.
Raith Rovers, Dunfermline, and Dundee sit second, third, and fourth in the Championship respectively, separated by just three points.
Dunfermline, whose trip to Stark's Park on Friday was due to be televised live on BBC Scotland, said on their website on Wednesday: "Following last Saturday's match, our club has unfortunately suffered a transmission of Covid into our football bubble.
"Since the weekend, we have cooperated fully with the respective authorities to determine fully the extent of the transmission and the individuals who are deemed to be affected."