Manchester City will be without Sam Mewis and Rose Lavelle for four games after they were called up to the United States squad for two matches against Colombia this month.
The US begin their training camp on 9 January, meaning the midfield pair will miss City's WSL matches against West Ham, Aston Villa and Brighton.
They will also miss their Continental Cup quarter-final against Chelsea.
Manchester United's Tobin Heath and Christen Press have not been selected.
It means the forwards will be available for the Women's Super League leaders' games against Everton, Chelsea and Birmingham during the same period.
Unbeaten United are four points clear at the top of the table, and eight ahead of last season's runners-up City, who have a game in hand.
Two-time World Cup winner and Ballon d'Or winner Megan Rapinoe has also been named in the 27-strong US squad.
The World Cup holders take on Colombia in Orlando on 18 and 22 January.
Full United States squad
Goalkeepers: Aubrey Bledsoe (Washington Spirit), Jane Campbell (Houston Dash), Ashlyn Harris (Orlando Pride), Alyssa Naeher (Chicago Red Stars)
Defenders: Alana Cook (Paris St-Germain), Abby Dahlkemper (North Carolina Courage), Tierna Davidson (Chicago Red Stars), Crystal Dunn (Portland Thorns FC), Emily Fox (UNC), Ali Krieger (Orlando Pride), Kelley O'Hara (Washington Spirit), Margaret Purce (Sky Blue FC), Becky Sauerbrunn (Portland Thorns FC), Emily Sonnett (Washington Spirit)
Midfielders: Julie Ertz (Chicago Red Stars), Lindsey Horan (Portland Thorns FC), Jaelin Howell (Florida State), Rose Lavelle (Manchester City), Catarina Macario (Stanford), Kristie Mewis (Houston Dash), Sam Mewis (Manchester City), Andi Sullivan (Washington Spirit)
Forwards: Carli Lloyd (Sky Blue FC), Mallory Pugh (Chicago Red Stars), Megan Rapinoe (OL Reign), Sophia Smith (Portland Thorns FC), Lynn Williams (North Carolina Courage)
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