Leaders Liverpool stretched 11 points clear of second-placed Leicester City as they eased aside Bournemouth and kept up their relentless pace at the top of the table.
Goals from Alex Oxlade-Chamberlain, Naby Keita and Mohamed Salah inflicted the Cherries' fifth successive defeat.
Defending champions Manchester City remain third, 14 points behind the leaders after losing 2-1 at home to local rivals Manchester United.
Elsewhere, Son Heung-min scored a wonderful solo goal as his Tottenham side ran out 5-0 winners at home to Burnley.
Captain Harry Kane netted twice with Lucas Moura and Moussa Sissoko completing the scoring.
In the day's only other 15:00 GMT kick-off, bottom side Watford claimed a point at home to Crystal Palace, with incoming manager Nigel Pearson watching from the stands.
Neither side looked like scoring in a grisly stalemate at Vicarage Road.
Earlier on Saturday, caretaker manager Duncan Ferguson guided Everton to a 3-1 win over Chelsea to the delight of a boisterous Goodison Park in their first match since Marco Silva's dismissal.