Austin FC has been announced as Major League Soccer's 27th club and will join the league in 2021.
It is the first major professional sports team in the Texas city - the 11th biggest by population in the US.
The team will play at their $225m (£175m) 20,000-seater stadium with work set to begin later this year.
"Austin is a thriving metropolitan city - the personification of what we mean when we say MLS is a league for a new America," said commissioner Don Garber.
Austin mayor Steve Adler added: "This is a historic day for Austin, as MLS becomes the first major league to plant roots in our beautiful city."
FC Cincinnati will start in the league later this year, while Nashville and David Beckham's Inter Miami are set to make their MLS debut in 2020.