Port of Togo and Morocco's Difaa el Jadida caused the biggest shocks on Sunday in the second leg of the African Champions League last-32 ties.
Port became the first Togolese side to make the group phase of Africa's elite club competition, knocking out Sudan's Al Hilal on away-goals.
Difaa el Jadida overcame former African champions AS Vita Club of the Democratic Republic of Congo with a 2-2 draw in Kinshasa to win 3-2 on aggregate.
Port knew they had a good chance to create history in the second leg of their tie against Al Hilal, having won their home leg 2-0 in Togo.
Al Hilal took the aggregate score to 2-1 after just five minutes through Geovane, but Port hit back immediately as Ayi struck two minutes later to make it 3-1 overall.
The hosts continued to try and claw their way back and were rewarded with further goals from Elnour and Bashier in the second half to make it 3-3 overall.
However, it was not enough for the Sudanese outfit as Port secured their passage into the group phase on the away-goals ruling.
Morocco's Difaa el Jadida - who earlier in the competition had achieved a record win over Benfica of Guinea-Bissau - took a slender 1-0 lead to Kinshasa for the return leg against Vita Club.
Mundele hit a brace for Vita Club but it was not enough, as a goal from Ahaddad and then a stoppage time equaliser from Nanah gave Jadida a 2-2 draw on the night, to win 3-2 on aggregate.
The clubs who qualified for the Champions League group phase will now be divided into four pools after a seeded draw, with the winners and runners-up from each group qualifying for the quarter-finals.
African Champions League last-32 second-leg results:
KCCA (Uganda) 1-0 Saint George (Ethiopia) (KCCA win 1-0 on aggregate)
Mbabane Swallows (Swaziland) 1-0 Zanaco (Zambia) (Swallows win 3-1 on aggregate)
Williamsville (Ivory Coast) 2-0 Wydad Casablanca (Morocco, holders) (Wydad win 7-4 on aggregate)
Mounana (Gabon) 1-3 Al Ahly (Egypt) (Ahly win 7-1 on aggregate)
Mouloudia Alger (Algeria) 6-0 MFM (Nigeria) (Mouloudia win 7-2 on aggregate)
Generation Foot (Senegal) 0-2 Horoya (Guinea) (Horoya win 4-1 on aggregate)
Township Rollers (Botswana) 0-0 Young Africans (Tanzania) (Rollers win 2-1 on aggregate)
Songo (Mozambique) 3-0 TP Mazembe (DR Congo) (Mazembe win 4-3 on aggregate)
Wits (South Africa) 1-0 Primeiro Agosto (Angola) (Tie ends 1-1 on aggregate. Primeiro win 3-2 on penalties)
Entente Setif (Algeria) 4-0 Aduana Stars (Ghana)(Setif win 4-1 on aggregate)
Esperance (Tunisia) 1-0 Gor Mahia (Kenya) (Esperance win 1-0 on aggregate)
Plateau Utd (Nigeria) 1-0 Etoile Sahel (Tunisia)(Etoile win 4-3 on aggregate)
Al Hilal (Sudan) 3-1 Port (Togo) (Tie ends 3-3 on aggregate. Port win on away goals)
ASEC Mimosas (Ivory Coast) 1-2 Zesco Utd (Zambia) (Tie ends 2-2 on aggregate. Zesco win on away goals)
V Club (DR Congo) 2-2 Difaa el Jadida (Morocco) (Jadida win 3-2 on aggregate)
Mamelodi Sundowns (South Africa) 2-0 Rayon Sports (Rwanda) (Sundowns win 2-0 on aggregate)
Winners qualify for group stage and losers drop to African Confederation Cup play-offs.