On another important day at the bottom of the table, Crystal Palace were the big winners, beating Huddersfield 2-0 to climb out of the relegation zone.
Bottom club West Brom lost 2-1 at Bournemouth to leave them 10 points from safety with seven matches left.
Stoke stay 19th after a 2-1 home loss to Everton. Charlie Adam was sent off for a challenge on Wayne Rooney.
In the late kick-off, Liverpool thrashed Watford 5-0, with Mohamed Salah bagging four of the goals.