Match ends, Hull City 1, Preston North End 2.
Callum Robinson scored a late goal to give Preston North End three points against Hull City at the KCOM Stadium.
Tom Barkhuizen gave North End the lead when, amid a scramble in the box, he fired home from a tight angle.
Hull levelled after the break through Jarrod Bowen, who slotted the ball past keeper Chris Maxwell from close range.
On the counter, Preston were rewarded with just two minutes left when Robinson headed into an empty net from Daryl Horgan's right-wing cross.
Preston's victory maintains the pressure on the Championship frontrunners as they made it seven games unbeaten and are fourth after the result.
It is the first time Alex Neil has won back-to-back away league matches as a manager since April 2015 during his time in charge of Norwich City.
Meanwhile Hull, who had won five of their past six home games against North End prior to Tuesday's encounter, lost for the fifth time in the league this season and slip to 17th.
Their winless run stretches to five games, with their last Championship victory coming against Bolton in August.
Hull City boss Leonid Slutsky:
"I say sorry to the supporters because I understand they must be disappointed because we don't bring results, I don't bring results. It's very difficult speaking about a performance when you concede in the last minute and it's not the first time.
"In this situation it's possible to lose confidence because everyone is frustrated now and it's very difficult, because each match is very close. In each match we have chances to win but we can't.
"When you don't win five matches in a row of course you lose confidence. It's a new team and results are important for developing."
Preston North End manager Alex Neil:
"It was a great result. I thought over the piece we deserved to win the game.
"I had a real decision as to whether I bust the game open with an aggressive substitute or being happy with a point.
"I made the decision to go for the game and they rewarded me by winning the match - one sub creating the goal and one sub scoring the goal."
- 1McGregorBooked at 37mins
- 29TomoriSubstituted forGrosickiat 45'minutes
- 21DawsonBooked at 36mins
- 28KingsleySubstituted forClarkat 25'minutes
- 16LarssonBooked at 24mins
- 25CampbellBooked at 37minsSubstituted forDickoat 84'minutes
- 14FisherBooked at 61mins
- 11JohnsonBooked at 90mins
- 19WelshSubstituted forRobinsonat 67'minutes
- 29BarkhuizenSubstituted forHorganat 78'minutes
- 9HugillSubstituted forHarropat 67'minutes
- James Linington
- Shots on Target
Second Half ends, Hull City 1, Preston North End 2.
Ola Aina (Hull City) wins a free kick on the left wing.
Foul by Alan Browne (Preston North End).
Attempt saved. Josh Harrop (Preston North End) right footed shot from the centre of the box is saved in the bottom left corner.
Daniel Johnson (Preston North End) is shown the yellow card.
Foul by Ola Aina (Hull City).
Callum Robinson (Preston North End) wins a free kick on the left wing.
Goal! Hull City 1, Preston North End 2. Callum Robinson (Preston North End) header from the left side of the six yard box to the top left corner. Assisted by Daryl Horgan with a cross.
Attempt missed. Kamil Grosicki (Hull City) right footed shot from outside the box misses to the right. Assisted by Jackson Irvine.
Allan McGregor (Hull City) wins a free kick in the defensive half.
Foul by Paul Huntington (Preston North End).
Foul by Michael Hector (Hull City).
Sean Maguire (Preston North End) wins a free kick on the right wing.
Substitution, Hull City. Nouha Dicko replaces Fraizer Campbell.
Offside, Preston North End. Callum Robinson tries a through ball, but Joshua Earl is caught offside.
Foul by Jarrod Bowen (Hull City).
Callum Robinson (Preston North End) wins a free kick in the attacking half.
Ola Aina (Hull City) wins a free kick in the defensive half.
Foul by Callum Robinson (Preston North End).