Match ends, Birmingham City Ladies 1, Manchester City Women 4.
World Player of the Year Carli Lloyd was among the scorers as Manchester City cruised past Birmingham to win the Women's FA Cup for the first time.
Lucy Bronze headed the opener following a free-kick and crossed for Izzy Christiansen to crash home the second.
Lloyd's header capped a fine 14-minute spell to make it 3-0 by the break.
Charlie Wellings' goal gave Birmingham brief hope, but Jill Scott's fierce shot sealed City's victory in front of a competition-record crowd at Wembley.
The 2016 Women's Super League champions are now in possession of all three main domestic honours - the first team to do so since Arsenal Ladies in 2011.
Birmingham had knocked out holders Arsenal and 2015 champions Chelsea to make the final, but the 2012 winners never looked like repeating that feat on their first trip to Wembley in front of 35,271 fans.
Four domestic honours in nine months?
Before 2014, Manchester City Women had never lifted a major trophy - but they are now closing in on a potential clean sweep of all four domestic honours in the space of nine months.
Having won the WSL and Continental Cup last year, they will hope to add the WSL Spring Series to their Women's FA Cup success.
Manchester City, who also reached the Champions League semi-finals in May, had never even played in the top flight when Birmingham won the FA Cup in 2012.
Man City's high press pays dividends
City's relentlessly aggressive pressing game and dominant defence laid the foundation for a ruthless victory which was as good as sealed by the interval.
Birmingham's inability to retain possession under persistent pressure led to them conceding territory and numerous free-kicks and corners, where City's set-piece superiority twice told in a one-sided first half.
Moments after a near-post corner almost brought an opening goal for Megan Campbell with a neat flicked effort, Bronze darted in to convert Campbell's inviting inswinging free-kick for a 1-0 lead.
Bronze then bustled Paige Williams out of possession and picked out Christiansen with a delightful cross.
Lloyd leaves her mark
City's preference to stretch play and attack down the flanks had meant that, despite being 2-0 up, Lloyd was a peripheral figure for the opening 30 minutes.
She had shown glimpses of her technical ability and vision but made her quality count when she rose above flapping Blues keeper Ann-Katrin Berger to head home another Campbell cross following a short corner.
City stayed in control despite facing an improved Blues side after the break, with the lively Nikita Parris having a shot tipped wide and Steph Houghton sending a header off target.
Birmingham were rewarded for their efforts through Wellings' curled effort, but Scott showed some nifty footwork to fire in a fourth goal after good work by substitute Toni Duggan.
'It's what dreams are made of'
Manchester City captain Houghton, who will also lead England at Euro 2017 this summer, described the FA Cup as "the one we were missing" after their final triumph.
"Credit to all the girls and all the staff, we've worked so hard," she told BBC Radio 5 live. "We've had a tireless schedule, but we were the best team on the day.
"The aim was to win as many trophies with this team as I could. To be captain of this club is unbelievable - but to win the FA Cup at Wembley, it's what dreams are made of."
B'ham City Women
- 25MannionBooked at 90mins
- 4CarterBooked at 89mins
- 11HegerbergSubstituted forPeplowat 83'minutes
- 2WilliamsSubstituted forStringerat 88'minutes
- 7AyisiSubstituted forWellingsat 64'minutes
Man City Women
- 20CampbellSubstituted forMcManusat 78'minutes
- 17ParrisSubstituted forStanwayat 71'minutes
- 14LawleySubstituted forDugganat 56'minutes
- Rebecca Welch
- Shots on Target
Second Half ends, Birmingham City Ladies 1, Manchester City Women 4.
Attempt missed. Georgia Stanway (Manchester City Women) right footed shot from outside the box is too high. Assisted by Carli Lloyd.
Attempt saved. Stephanie Houghton (Manchester City Women) right footed shot from outside the box is saved in the centre of the goal.
Aoife Mannion (Birmingham City Ladies) is shown the yellow card for a bad foul.
Foul by Aoife Mannion (Birmingham City Ladies).
Carli Lloyd (Manchester City Women) wins a free kick in the attacking half.
Offside, Manchester City Women. Carli Lloyd tries a through ball, but Toni Duggan is caught offside.
Jessica Carter (Birmingham City Ladies) is shown the yellow card for a bad foul.
Abbie McManus (Manchester City Women) wins a free kick in the defensive half.
Foul by Jessica Carter (Birmingham City Ladies).
Substitution, Birmingham City Ladies. Abbey-Leigh Stringer replaces Paige Williams.
Foul by Jessica Carter (Birmingham City Ladies).
Isobel Christiansen (Manchester City Women) wins a free kick in the defensive half.
Attempt blocked. Charlie Wellings (Birmingham City Ladies) right footed shot from outside the box is blocked.
Corner, Manchester City Women. Conceded by Paige Williams.
Substitution, Birmingham City Ladies. Chloe Peplow replaces Andrine Hegerberg.
Lucy Bronze (Manchester City Women) wins a free kick on the right wing.
Foul by Kerys Harrop (Birmingham City Ladies).
Attempt missed. Ellen White (Birmingham City Ladies) right footed shot from the centre of the box is high and wide to the left. Assisted by Jessica Carter with a cross.