Bournemouth's on-loan midfielder Jack Wilshere will not play again this season after suffering a fractured leg.
The 25-year-old England international, on a season-long loan from Arsenal, was injured in the Cherries' 4-0 defeat by Tottenham on Saturday.
"It's a big blow to lose Jack," Bournemouth manager Eddie Howe said.
Wilshere has made 29 Premier League appearances this season for the club, without scoring, after joining them on transfer deadline day in August.
Scans have revealed a hairline crack in Wilshere's left fibula and he will miss Bournemouth's last five games of the season and return to Arsenal for further treatment.
Gunners manager Arsene Wenger said he expects the midfielder to return in July for pre-season training.
"I felt sad when he was injured again," the Frenchman said. "Jack is a great football player with a great football brain. His career has been stopped by many injuries."
Wilshere was substituted after 56 minutes of the game at White Hart Lane following a challenge with Tottenham striker Harry Kane.
"We've loved working with him since he arrived in August," Howe added. "He's made a huge contribution to our season and we wish him a quick recovery."