Match ends, Newport County 1, Cambridge United 2.
Bottom-placed Cambridge struck twice in the second half to clinch their first win of the season in League Two.
Rhys Healey's header gave Newport a 10th-minute lead on his full debut.
Adam McGurk almost equalised when his free-kick hit the crossbar, and Cambridge were eventually back on terms when Uche Ikpeazu fired in from Newport old boy Medi Elito's long ball.
And Cambridge claimed all the points when Luke Berry drove the ball home after a scramble.
The result sees County drop into the bottom two - ahead of Cambridge on goal difference.
Newport manager Warren Feeney said: "It's the story of our season to be honest.
"We can't keep giving the goals we're giving away. We can work at things all week but when you cross that white line that's the disappointing thing.
"But listen, I take full responsibility for everything.
"You can stand here and say this or say that, but the results don't lie. When we get up tomorrow it will say 2-1 to Cambridge."
- 28Grego-CoxBooked at 74mins
- 12TozerBooked at 58mins
- 8RandallSubstituted forSheehanat 79'minutes
- 19HealeyBooked at 30mins
- 9ParkinSubstituted forJacksonat 70'minutes
- 6LeggeBooked at 60mins
- 20ClarkBooked at 81mins
- 19GoslingSubstituted forTaylorat 45'minutes
- 10WilliamsonSubstituted forIkpeazuat 45'minutesSubstituted forCoulsonat 90+7'minutes
- 17McGurkBooked at 58mins
- Nick Kinseley
- Shots on Target
Second Half ends, Newport County 1, Cambridge United 2.
Foul by Reece Grego-Cox (Newport County).
Harrison Dunk (Cambridge United) wins a free kick on the left wing.
Substitution, Cambridge United. Josh Coulson replaces Uche Ikpeazu.
Corner, Newport County. Conceded by Harrison Dunk.
Foul by Rhys Healey (Newport County).
Brad Halliday (Cambridge United) wins a free kick on the left wing.
Uche Ikpeazu (Cambridge United) wins a free kick on the right wing.
Foul by Dan Butler (Newport County).
Corner, Cambridge United. Conceded by Scot Bennett.
Goal! Newport County 1, Cambridge United 2. Luke Berry (Cambridge United) right footed shot from the left side of the six yard box to the centre of the goal following a set piece situation.
Foul by Sean Rigg (Newport County).
Medy Elito (Cambridge United) wins a free kick on the right wing.
Attempt missed. Josh Sheehan (Newport County) left footed shot from outside the box misses to the right.
Max Clark (Cambridge United) is shown the yellow card for a bad foul.
Josh Sheehan (Newport County) wins a free kick in the attacking half.
Foul by Max Clark (Cambridge United).
Substitution, Newport County. Josh Sheehan replaces Mark Randall.
Attempt missed. Kyle Cameron (Newport County) header from the centre of the box is too high.