Match ends, Udinese 0, Inter Milan 4.
Mauro Icardi scored twice as Inter Milan dispatched Udinese to extend their lead at the top of Serie A.
Roberto Mancini's side secured their sixth win in seven games to go four points ahead of Fiorentina, who play champions Juventus on Sunday.
Skipper Icardi fired Inter into a 23rd-minute lead before Stefan Jovetic chipped in the second before the break.
Icardi then got his second seven minutes from time before substitute Marcelo Brozovic curled in the fourth.
Udinese came into the match unbeaten in their previous five home games and started well but were then punished for a succession of defensive mistakes.
Top scorer Icardi pounced on a weak pass from Bruno Fernandes to advance and claim his fifth goal of the season with an angled shot past Karnezis.
And veteran sweeper Maurizio Domizzi, 35, then gifted Jovetic possession for the former Manchester City striker to claim his fourth goal of the campaign eight minutes later.
Inter, who have not conceded a goal in their last six wins, equalled their biggest win of the season with two late goals.
Argentina international Icardi collected another misplaced pass to hit a fierce shot inside the near post before Brozovic cut in to claim the goal of the game with a curling effort into the top corner.
Elsewhere, Palermo beat fellow strugglers Frosinone 4-1 to pull clear of the relegation zone, while Bologna won 1-0 at Genoa.
The game between Sassuolo and Torino was postponed because of fog.
- 11DomizziBooked at 65mins
- 16IturraSubstituted forPericaat 70'minutes
- 8Bruno FernandesBooked at 52minsSubstituted forde Mattos Filhoat 56'minutesBooked at 89mins
- 21Andrade dos Santos
- 10Di NataleSubstituted forAguirreat 79'minutes
- 19dos Santos Torres
- 23de Mattos Filho
- 53Nassir Al-Tameemi
- 95Evangelista Santana de Oliveira
- 12TellesBooked at 15mins
- 44PerisicBooked at 7mins
- 22LjajicBooked at 21minsSubstituted forNunes Jesusat 82'minutes
- 9IcardiSubstituted forManajat 90'minutes
- 10JoveticSubstituted forBrozovicat 61'minutes
- 5Nunes Jesus
- 6Pires Ribeiro
- Davide Massa
- Shots on Target
Second Half ends, Udinese 0, Inter Milan 4.
Attempt missed. Cyril Théréau (Udinese) right footed shot from the centre of the box misses to the right. Assisted by Maurizio Domizzi with a headed pass following a corner.
Corner, Udinese. Conceded by Samir Handanovic.
Attempt saved. Stipe Perica (Udinese) header from the centre of the box is saved in the bottom left corner. Assisted by Iván Piris with a cross.
Maurizio Domizzi (Udinese) wins a free kick on the left wing.
Foul by Rey Manaj (Inter Milan).
Attempt saved. Rodrigo Aguirre (Udinese) left footed shot from a difficult angle on the left is saved in the centre of the goal. Assisted by Marquinho.
Attempt missed. Rey Manaj (Inter Milan) right footed shot from the centre of the box misses to the right. Assisted by Marcelo Brozovic with a cross.
Foul by Francesco Lodi (Udinese).
Rey Manaj (Inter Milan) wins a free kick in the defensive half.
Stipe Perica (Udinese) wins a free kick in the attacking half.
Foul by Juan Jesus (Inter Milan).
Attempt saved. Alex Telles (Inter Milan) left footed shot from outside the box is saved in the top right corner.
Substitution, Inter Milan. Rey Manaj replaces Mauro Icardi.
Marquinho (Udinese) is shown the yellow card for a bad foul.
Foul by Marquinho (Udinese).
Martín Montoya (Inter Milan) wins a free kick in the attacking half.
Goal! Udinese 0, Inter Milan 4. Marcelo Brozovic (Inter Milan) right footed shot from outside the box to the top right corner. Assisted by Fredy Guarín.
Cyril Théréau (Udinese) wins a free kick in the attacking half.