Liverpool Ladies defender Becky Easton could miss the rest of the season after sustaining a broken arm in Sunday's 2-0 Continental Cup loss.
The 41-year-old was injured after a coming together with Manchester City forward Toni Duggan and later tweeted that her arm had been stood on.
Liverpool manager Matt Beard said the injury "summed our season up".
"It's been a frustrating season right the way across the board with illness and injuries," Beard told BBC Sport.
"We get one player back and then we lose a player. We're going to be another player down for a few months now".
Liverpool have four Women's Super League One fixtures still to play, as well as being through to the Continental Cup quarter-finals and starting their Champions League campaign in October.
The club have lost a number of key players to long-term injuries this season and Easton joins Fara Williams, Asisat Oshoala and Corina Schroder in the treatment room.
Manchester City also had to substitute England duo Lucy Bronze and Duggan off during the match after the pair were injured following tackles.
City boss Nick Cushing said both players had been removed as a "precaution" but expressed concern over the strength of some challenges in the women's game this season.
"I do think that lately in this league there's been some really potentially bad tackles," said Cushing.
"But the referees are there to referee the game and I'm more worried about the performance of my team."