Second Half ends, Chile 1, Uruguay 0.
Chile 1-0 Uruguay
Hosts Chile moved into the Copa America semi-finals as Mauricio Isla's late winner knocked nine-man holders Uruguay out of the tournament.
Chile dominated a bruising contest, Eduardo Vargas and Arturo Vidal both going close before Edinson Cavani was sent off for a second yellow card.
Uruguay held out until the 82nd minute when Isla fired home from 16 yards.
In the closing moments of an ugly game Uruguay defender Jorge Fucile was red-carded for a second caution.
Chile will now face the winners of Friday's match between Bolivia and Peru (00:30 BST) for a place in the final.
Uruguay's tournament ended in disgrace in a stormy game that saw six yellow cards in addition to two reds at Estadio Nacional in Santiago.
The biggest talking point before Isla's winner was Cavani's first red card for Uruguay on his 76th appearance for his country.
Having been shown a yellow card for confronting a linesman, the 28-year-old Paris St-Germain forward was ordered off after TV pictures appeared to show Gonzalo Jara putting a hand on his buttocks.
Defender Jara theatrically fell to the ground in response to a raised hand from Cavani, whose father was involved in a fatal car crash in Uruguay this week.
He argued with the referee for several minutes before finally being persuaded to leave the pitch.
Uruguay self-destructed after falling behind, Fucile sent off for a second booking with two minutes remaining after bringing down Alexis Sanchez.
The match was then halted for several minutes after Uruguay's players surrounded the referee and linesman, and officials and players from both sides scuffled on the field.
Chile, who dominated the match with 80% possession, have never won the Copa America since its inception in 1916.
The other two quarter-finals feature Argentina against Colombia (00:30 BST) on Saturday and Brazil versus Paraguay on Sunday (00:30 BST).
- 4IslaBooked at 43mins
- 18JaraBooked at 63mins
- 21DíazSubstituted forFernándezat 71'minutes
- 10ValdíviaBooked at 18minsSubstituted forPizarroat 85'minutes
- 11VargasSubstituted forPinillaat 71'minutesBooked at 84mins
- 22Henriquez Iturra
- 16Pereira PáezBooked at 67mins
- 2Giménez de Vargas
- 4FucileBooked at 88mins
- 5SánchezSubstituted forRodríguez Portilloat 85'minutes
- 17Arévalo Rios
- 9RolanSubstituted forHernándezat 58'minutes
- 21CavaniBooked at 63mins
- 10de Arrascaeta
- 13G Silva
- 22Rodríguez Portillo
- 23M Silva
- Sandro Meira Ricci
- Shots on Target
Corner, Chile. Conceded by Fernando Muslera.
Attempt saved. Arturo Vidal (Chile) right footed shot from the centre of the box is saved in the bottom right corner. Assisted by David Pizarro.
Foul by Mauricio Pinilla (Chile).
Egidio Arévalo Rios (Uruguay) wins a free kick in the defensive half.
Offside, Chile. Arturo Vidal tries a through ball, but Alexis Sánchez is caught offside.
Delay over. They are ready to continue.
Delay in match (Chile) for fighting.
Second yellow card to Jorge Fucile (Uruguay) for a bad foul.
Alexis Sánchez (Chile) wins a free kick on the right wing.
Foul by Jorge Fucile (Uruguay).
Substitution, Uruguay. Jonathan Rodríguez replaces Carlos Sánchez.
Substitution, Chile. David Pizarro replaces Jorge Valdívia.
Mauricio Pinilla (Chile) is shown the yellow card for a bad foul.
Foul by Mauricio Pinilla (Chile).
Giménez (Uruguay) wins a free kick in the defensive half.
Jorge Valdívia (Chile) wins a free kick in the attacking half.
Foul by Egidio Arévalo Rios (Uruguay).
Gonzalo Jara (Chile) wins a free kick in the defensive half.
Foul by Abel Hernández (Uruguay).