Queen of the South 0-1 Hamilton
Championship leaders Hamilton extended their unbeaten run to five games as Mickael Antoine-Curier scored the winner in Dumfries.
The striker controlled Tony Andreu's cut-back before finishing past Queen of the South goalkeeper Zander Clark for his third goal of the season.
Hamilton goalkeeper Kevin Cuthbert prevented an equaliser just with a superb save from a Derek Lyle header.
The striker had another header cleared off the line by Stephen Hendrie.
Eamonn Brophy almost gave Hamilton a two-goal cushion minutes after replacing Antoine-Curier.
However, his miss did not prove crucial as Hamilton went home with all three points and gained revenge for last weekend's Scottish Cup defeat.