Wales' Under-21 squad face Moldova at Parc Y Scarlets in their opening World Championship qualifying match.
Intermediate Manager Geraint Williams takes charge of his first competitive fixture as Wales bid to qualify for their first major tournament.
Crystal Palace midfielder Johnny Williams has been promoted to the senior squad and will miss the match.
A place at the Under-21 World Championships in the Czech Republic is on offer for the group winners.
Despite beating Iceland 3-0 in a warm-up match in February, Wales have suffered consecutive defeats in competitive action.
Their opponents Moldova finished their previous qualifying campaign strongly with a win over Albania and a draw in Russia.
"They (Moldova) are a strong side who work very hard for each other," Williams told the Football Association of Wales website.
"They have a target man who plays for Dynamo Kiev and he will be a handful, so we know exactly what they will bring to the table.
"We have to match the work-rate, stick to our game plan and be positive."
Both Wales and Moldova are joined in Group One by England, Finland, Lithuania and San Marino.
Wales team V Moldova: Danny Ward (Liverpool), Kieron Freeman (Derby County), Jonathan Meades (AFC Bournemouth), Lee Lucas (Swansea City), Scott Tancock (Swansea City), Joe Walsh (Crawley Town), Wes Burns (Bristol City), Emyr Huws (Manchester City), Jake Cassidy (Wolverhampton Wanderers), Tom Lawrence (Manchester United), Billy Bodin (Torquay United).
Subs: Connor Roberts (Cheltenham Town), Alex Nicholson (Newcastle United), Theo Wharton (Cardiff City), George Ray (Crewe Alexandra), Louis Thompson (Swindon Town), Ellis Harrison (Bristol Rovers), Robert Ogleby (Wrexham).