Ballymena United manager Glenn Ferguson will face his old club Linfield in the quarter-finals of the League Cup.
In Wednesday's draw, holders Crusaders have been paired with Premiership strugglers Lisburn Distillery while Cliftonville entertain Portadown.
The other game sees Glenavon player-manager Gary Hamilton pitched against his former club Glentoran in a tasty tie at Mourneview Park.
The matches are to be played on Monday, 5 November.
Linfield grabbed a late win away to Coleraine in the third round on Tuesday thanks to Michael Carvill's extra-time goal, while Ballymena United saw off Championship side H&W Welders.
Holders Crusaders made the last eight by fighting back from 2-0 down to beat Carrick Rangers 4-3 on Tuesday night, David Gibson snatching an 89th-minute winner for Stephen Baxter's side.
Premiership leaders Cliftonville crushed Ballinamallard 5-0, Portadown were 4-0 winners away to Bangor, Glentoran beat Institute on penalties, Glenavon shaded a 2-1 win over Dergview and Lisburn Distillery trounced Coagh United 9-0.
Irn-Bru League Cup quarter-finals
Ballymena United v Linfield
Cliftonville v Portadown
Crusaders v Lisburn Distillery
Glenavon v Glentoran