Macclesfield Town condemned Blue Square Bet Premier newcomers Dartford to a third consecutive defeat.
The Silkmen went ahead before the break when Dartford defender Tom Champion headed into his own net.
Matthew Barnes-Homer and Jack Mackreth both went close to extending the lead, but hit the post and bar respectively.
But the hosts did wrap up the victory when Mark Arber was punished for handball and Charlie Henry slotted in the resulting penalty.
VIEWS FROM THE DRESSING ROOM
Dartford manager Tony Burman told BBC Radio Kent:
"In the first 30 minutes we've had chances to be 2-0 up, we did really well, they're a good passing side.
"We caught them enough times, that's when we got our chances but you have to punish the opposition.
"One we went a goal down we put pressure on ourselves even more, but I felt the game was there to get something out of it.
"What I wanted when we made the subs didn't happen, the guys have done well but we went a goal down, you might as well go for it."