Francois Zoko netted his sixth goal in as many games as Carlisle United eased past Leyton Orient.
The striker's low shot put the hosts ahead inside a minute and Matty Robson added the second from a free-kick.
Tom Taiwo's dipping shot from the edge of the area made it 3-0 at half-time and James Berrett skipped past two defenders to slot home the fourth.
Substitute Jamie Cureton nodded in Dean Cox's free-kick late on but it was a mere consolation for the O's.
VIEWS FROM THE DRESSING ROOM
Carlisle United assistant boss Graham Kavanagh told BBC Radio Cumbria:
"I think today was a really professional performance, very strong, very solid and I think the early goal really settled us down.
"To come away with a 4-1 victory, against a side who have been on a good run of form, is a great day's work.
"It gives us a good goal difference, we were in minus so we now jump into plus and we also cement ourselves in the top six."
Leyton Orient manager Russell Slade told BBC London 94.9:
"I'm disgusted with the first half and I thought it was really poor. The manner in which we conceded the goals has really upset me, I feel sick.
"A team that kept a clean sheet against Charlton and a clean sheet against Stevenage but defends like that in the first minute, I don't know where that came from.
"We were much better in the second half but the game was gone - it was already over by then. It is difficult to come back from 3-0 and we huffed and puffed but the damage was already done in the first period."