Bristol City striker Ryan Taylor and defender Nicky Hunt have been ruled out of action for six-to-eight weeks because of injury.
Both players were forced off the field in the Gloucestershire Senior Challenge Cup win over Mangotsfield on Tuesday.
Striker Taylor, 23, has broken his fifth metatarsal while defender Hunt, 28, has suffered knee cartilage damage.
Manager Derek McInnes told the club website: "Obviously we're disappointed to lose the two lads."
He continued: "It's strange because Ryan says he's suffered a metatarsal injury on his other foot before, and Nicky likewise on his other knee.
"The two lads are disappointed because they wanted the opportunity to show they are worthy of a place in the first team and now they are set for up to two months out on the sidelines."