Somalia earned a 0-0 draw with Ethiopia in the only 2014 World Cup qualifier to be played on Saturday.
The game took place in Djibouti and the return leg of this preliminary tie will be in Addis Ababa on Wednesday.
In Friday's matches, Somalia's hosts - Djibouti - were themselves beaten by visitors Namibia.
Equatorial Guinea and Lesotho earned home victories but elsewhere it was away teams who dominated, with big wins for Congo Brazzaville and Kenya.
Namibia's Brave Warriors broke the deadlock in the 14th minute of the first-leg of the preliminary game through South Africa-based striker Rudolf Bester.
They doubled their lead in the 52nd minute before Henrico Boates made it 3-0 two minutes later.
Heinrick Isaacs found the target late in the game to seal the victory.
Sao Tome e Principe suffered a miserable return to international football after they were crushed 5-0 by Congo in their game in Sao Tome.
The home side were making their first international appearance in over eight years and they looked to have lost their rhythm following their long absence.
Two goals by Harris Tchilimbou helped the Red Devils to the emphatic victory at the Estadio 12 de Julho.
But it was Christopher Missilou who put Congo in the lead with a third minute strike before Tchilimbou doubled the lead moments later.
Francis Malonga put them in firm control with a 32nd mintue goal before Prince Oniangue made it 4-0 ten minutes after the break.
Tchilimbou sealed his brace in the 70th minute to seal the misery for Sao Tome e Principe.
Kenya also secured a big away win as the Harambee Stars thrashed Seychelles 3-0 in Port Victoria to boost their chances of advancing.
The home side provided a strong resistance until Pascal Ochieng broke the deadlock four minutes before the break.
Kevin Kimani made it 2-0 in the 75th minute before France-based striker Dennis Oliech sealed the win with minutes remaining.
Goals from Alain Kaluyituka Dioko, Tresor Mputu and Gladys Bokese helped DR Congo to a 3-1 win away in Swaziland with Mamba Mndeni getting the consolation for the Shilangu.
Meanwhile, Mozambique boosted their hopes of reaching the group phase thanks to their 1-0 away win over Comoros on Friday.
A second-half penalty converted by Miro secured the victory for the Mambas.
A late strike by Bakari Hamadi helped Tanzania to a 2-1 victory over Chad in N'Djamena.
The Taifa Stars broke the deadlock in the 11th minute through Mrisho Ngasa but the home side responded a minute later thanks to an effort by Mahamat Ahmat Labo.
But with just ten minutes remaining, Hamadi struck to secure victory for the visitors.
Rwanda played out to 1-1 draw in their clash with Eritrea in Asmara on Friday.
The home side took the lead in the first half before the Wasps rallied to draw level after the break.
It was the first game for Rwanda coach Milutin Sredojevic who took over the squad last month following the resignation of Sellas Tetteh.
Lehlomela Ramabele scored late in Lesotho's 1-0 win over Burundi, giving the tiny southern African enclave a chance at rubbing shoulders with African giants Ivory Coast and Ghana in the main qualifying competition.
Togo's 1-1 draw in Guinea-Bissau means it has work to do in next week's return leg to make sure its doesn't suffer an embarrassing early exit from qualifying.
The second legs of the preliminary qualifiers take place on Tuesday 15 November, save for the Ethiopia-Somalia match which takes place on Saturday.
The 11 overall winners will join Liberia, who received a bye when cash-strapped Mauritius withdrew, will advance to the group phase of the competition next June.
That is when Africa's top 28 nations begin their campaign, with a total of 10 four-team groups advancing the winners to the third and final round of qualifying.
In all, Africa will stage 152 qualifiers to determine which five teams will reach the 2014 World Cup.
Five teams will represent Africa at the first World Cup staged in Brazil since 1950.