Port Vale's John McCombe is hoping to defeat his brother Jamie in the Carling Cup tie between Vale and Huddersfield Town at Vale Park on Tuesday.
It is the first time that the siblings will have played against each other.
"I've spoken to him about it but we've been concentrating on our first matches," McCombe told BBC Radio Stoke.
"He'll get a few phone calls if we get one over on them and if he's marking me at corners, to get past him and get a goal would be great."
The 26-year-old defender, who has played over 100 league games for Vale, started his career with Huddersfield.
"It's obviously a club that I've got a lot of connections with," he said. "I currently live in Huddersfield as well so a lot of my friends and neighbours are fans."
"It's a big game and hopefully we'll get through to the next round."
Vale have an excellent recent record in the Carling Cup, defeating three Championship teams in the competition in the last two seasons.
Micky Adams' side made it to round three in 2009/10 courtesy of their victories over both Sheffield clubs, while they won 3-1 at eventual Championship winners QPR in the first round last season before losing 6-0 at Fulham.
"We know it's going to be a tough match [against Huddersfield] but we know we're more than capable of getting a victory," said McCombe.
"Over the last few years, we've performed quite well in the Carling Cup, beating a few Championship teams.
"It will be another good test for us against a good League One team that will be pushing for promotion this year."
Vale started the season with a 2-2 draw against Football League newcomers Crawley, while Huddersfield drew 1-1 at home to promoted Bury.
BBC Radio Stoke will have live commentary of Port Vale v Huddersfield on 94.6FM from 1945 BST on Tuesday, 9 August.