Oxford United will play an Everton XI and Birmingham City as part of their pre-season preparations.
United will also face League One side MK Dons and non-league clubs Didcot Town, Brackley Town, and Thame United.
In addition to their domestic friendlies Oxford will play in a pre-season tour in the United States.
U's boss Chris Wilder told the club website: "We have three high-profile matches, which will give the fans a chance to see our new signings."
Wilder added: "Obviously we have the tour to the USA and three matches here [at Kassam Stadium] followed by some local games.
"We feel we have got the balance right with the standard of opposition we are due to play."