Mark Cavendish was beaten in a sprint finish by German Marcel Kittel in the one-day Scheldeprijs race.
Manxman Cavendish, riding for Team Dimension Data, was well positioned on the wheel of Kittel entering the finishing straight in Belgium.
But the Etixx-Quick-Step rider narrowly held on to win in four hours 54 minutes and five seconds - his fourth win in the event in the past five years.
Germany's Andre Greipel, riding for Lotto-Soudal, was third.
Cavendish was bidding for a fourth victory in the race himself, having won in 2007, 2008 and 2011.
Scheldeprijs final leading positions (Antwerp-Schoten 207.8km):
1 Marcel Kittel (Ger) Etixx-Quick-Step 4hrs 54mins 05secs
2 Mark Cavendish (Gbr) Dimension Data
3 Andre Greipel (Ger) Lotto-Soudal
4 Edward Theuns (Bel) Trek-Segafredo
5 Niccolo Bonifazio (Ita) Trek-Segafredo
6 Danny van Poppel (Ned) Team Sky
7 Nikias Arndt (Ger) Team Giant-Alpecin
8 Wouter Wippert (Ned) Cannondale Pro Cycling
9 Dylan Groenewegen (Ned) Team LottoNL-Jumbo
10 Daniel McLay (Gbr) Fortuneo-Vital Concept all at same time
79 Scott Thwaites (Gbr) Bora-Argon 18 at 51secs
113 Adam Blythe (Gbr) Tinkoff Team 3mins 05secs
122 Luke Rowe (Gbr) Team Sky 4mins 10secs