Nottinghamshire director of cricket Mick Newell says bowler Luke Fletcher is suffering from back spasms and may be "struggling" for the weekend.
Fletcher sent down only 12 overs in Yorkshire's first innings this week and did not bowl in the second innings of the drawn match at Headingley.
Notts begin a Championship match with Middlesex at Trent Bridge on Saturday.
"We need to look at him and consider our options if he's struggling," Newell told BBC Radio Nottingham.
"He had a back spasm in the first innings and has been struggling for a few days now.
"He has been struggling since a six-hour drive to Brighton last week and that's not really helped him."
Notts play a T20 Blast game at home to Birmingham Bears on Friday night, but Fletcher is not in Newell's short-format plans at the moment.
The England selector explained how he hopes to keep his players fresh at a busy time in the season, with the majority of fast bowlers only playing in one form of the game at the moment - although Ajmal Shahzad does play in both formats.
"We are trying to keep (Peter) Siddle, (Andre) Adams and Fletcher fresh for four-day cricket at the moment and we're backing (Harry) Gurney, (Andy) Carter and Shahzad to do the work for us in Twenty20 matches," added Newell.