|Friends Life t20, Uxbridge|
|Gloucestershire 254-3 (20 ovs) beat Middlesex 149-8 (20 ovs) by 105 runs|
Kevin O'Brien and Hamish Marshall both hit centuries as Gloucestershire posted the highest Twenty20 total in England against Middlesex at Uxbridge.
O'Brien hit 11 sixes in his 119 off 52 balls as he and Marshall (102 off 54 balls) put on 192 for the first wicket in their side's 254-3.
That beat the 250-3 Somerset made against Gloucestershire in 2006.
Middlesex were never in the hunt as they made 149-8 to lose by 105 runs, Jon Lewis taking 3-31 for the visitors.
It was the biggest runs defeat Middlesex have suffered in the history of the format, and Gloucestershire's biggest margin of runs victory.
As well as being the highest total in English Twenty20 history, Gloucestershire's score was also the second highest in the history of the format, falling six runs short of the 260-6 Sri Lanka made against Kenya in Johannesburg in September 2007.
The opening stand of 192 between O'Brien and Marshall was the highest for any wicket in Twenty20 cricket in England, and has only been bettered by the 206 put on by Adam Gilchrist and Shaun Marsh for Kings XI Punjab against Royal Challengers Bangalore in this year's Indian Premier League.
It was also the first time two players have scored centuries in the same Twenty20 innings, with O'Brien's score also the highest in the competition by a Gloucestershire batsman.
Middlesex captain Dawid Malan told BBC London 94.9:
"They played ridiculously well, we didn't bowl very well, we didn't field very well and if we took our catches early on it could have been a different game.
"If you drop three catches in the first six overs it doesn't make it easy, especially when both blokes go on and score a hundred.
"We could have reduced them to 200 and had something to chase, but we weren't very good and no excuses."