Heavyweight David Price will fight for the European title against Germany's Erkan Teper on 26 June, his first UK bout in almost two years.
Liverpudlian Price, 31, will fight in his home city's Echo Arena, the scene of his last contest on British soil - a loss to American Tony Thompson in 2013.
British super-middleweight Callum Smith meets Christopher Rebrasse on the bill.
And fellow Briton Tony Bellew, 32, will contest his fourth fight at cruiserweight against Czech Lubos Suda.
A win for 32-year-old Bellew could pave the way for a shot at IBF world champion Yoan Hernandez in the Autumn.
Frenchman Rebrasse has three defeats as a pro - his last at the hands of George Groves in September - and victory for undefeated Smith, 25, should land him a world title eliminator.
Price's career stalled with back-to-back defeats by Thompson at the Echo Arena in 2013. Since then he has won four times abroad, setting up a meeting with undefeated Teper.
"It's behind me and I've moved on," said Price, who has 19 wins from 21 fights. "The one-punch knockout artist is still there, but now I'm a more polished boxer. I'm more relaxed and I'm enjoying my time in the ring."
Elsewhere on the card, Liverpool's Rocky Fielding, 27, will look to extend his run of 20 wins from as many fights against American Brian Vera.