Confederation of African Football (Caf) president Ahmad is to spend five days in hospital in Cairo after contracting coronavirus.
The 60-year-old tested positive for Covid-19 on Friday, two days after flying into the Egyptian capital from Morocco where he had attended Sunday's Confederation Cup final.
"We have just learned that the president is to be hospitalised for five days on our doctor's recommendation," Caf Communications Director Alex Siewe told BBC Sport Africa.
"Patients isolate better in hospital."
Earlier on Friday, African football's ruling body announced that the Malagasy was to self-isolate for two weeks.
"After his arrival in Cairo on Wednesday, Ahmad presented mild flu symptoms, and submitted to the Covid-19 protocol," said a Caf statement.
"Today, the test results are positive. The President (must) immediately self-isolate for at least the next 14 days at his hotel.
"All those who have come into contact with Ahmad over the past seven days - especially during his trip to Morocco for the Confederation Cup - have been informed and requested to take the necessary measures."
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Ahmad was in attendance on Sunday for the Confederation Cup final in Rabat, where Moroccans RS Berkane lifted the trophy.
Fifa president Gianni Infantino, who is in self-isolation after contracting coronavirus himself earlier this week, has written to Ahmad to express support.
"In the name of the great international football community and myself, I would like to send you my best wishes for a swift and complete recovery," Infantino said on Friday.
The news caps a turbulent week for Ahmad who announced his candidacy for a second term in office on Wednesday, the same day as it was reported that the Malagasy may be prevented from contesting March's elections.
BBC Sport Africa understands that Ahmad has been found to have breached various codes of ethics, with sentencing expected to happen by the end of November.
Any ban is likely to rule out his chances of standing for re-election, given he would have to pass an eligibility test to resume his place on the Fifa Council. Ahmad has previously strongly denied any wrongdoing.