Jac is back on form after her surgery and determined to prove she is a doctor not a patient. Dom and Lofty find themselves at cross purposes.
Jac's fully recovered and is fighting to prove she's back at the top of her game. But can she convince Professor Gaskell of that as they treat a patient together?
Dom plans a holiday with Lofty, while Lofty plans something much bigger - only for Dom's mum Carole to get caught in the middle and make Dom doubt his relationship.
Essie connects with a fellow patient, Julie, who helps her see Holby in a whole new light.
Timings (where shown) are from the start of the programme in hours and minutes
|Ben 'Lofty' Chiltern||Lee Mead|
|Dominic Copeland||David Ames|
|Jac Naylor||Rosie Marcel|
|Adrian 'Fletch' Fletcher||Alex Walkinshaw|
|Donna Jackson||Jaye Jacobs|
|John Gaskell||Paul McGann|
|Essie Di Lucca||Kaye Wragg|
|Sacha Levy||Bob Barrett|
|Nicky McKendrick||Belinda Owusu|
|Henrik Hanssen||Guy Henry|
|Roxanna MacMillan||Hermione Gulliford|
|Xavier 'Zav' Duval||Marcus Griffiths|
|Ric Griffin||Hugh Quarshie|
|Carole Copeland||Julia Deakin|
|Julie Bloom||Natasha Joseph|
|Cassie Lincombe||Ruby Bentall|