Today's running order
Pope Francis arrives in Africa tomorrow for a three-country visit, ending at the Central African Republic, a country which has been tearing itself apart for decades. The religious side to the crisis is a relatively recent phenomenon - Alastair Leithead reports from the capital Bangui.
Scientists have used a groundbreaking gene-editing technique to introduce a malaria-blocking gene into mosquitos. Professor Luke Alphey is group leader in Arthropod Genetics at the Pirbright Institute.
Brussels is still on lockdown as the security operation against suspected Islamists continues. Speaking on the programme is Alain Destexhe, a senator from Brussels.
The Children's Commissioner for England says the number of children being sexually abused is much higher than previously thought, estimating only one in eight comes to the attention of the authorities. Speaking on the programme is Anne Longfield, Children’s Commissioner.
Welsh rugby officials have defended their record on doping after the latest figures showed a third of the UK's 52 banned athletes are all rugby league or union players from Wales. Hywel Griffith is the BBC’s Wales correspondent.
Francois Hollande is in Washington to discuss responses to the Paris attacks. Speaking on the programme is Jeremy Bowen, the BBC’s Middle East editor, and Paddy Ashdown, the Liberal Democrat peer.
It's an intriguing idea - pick a famous album and then turn each song title into the subject of a speech to be delivered by an expert in the relevant field. This is the premise of The Concept Album Talks, which took place in Central London last night. Our Entertainment correspondent Colin Paterson was in the audience.
The government has announced today its health spending plans for the next few years ahead of Wednesday's comprehensive spending review. Anita Charlesworth is chief economist at the Health Foundation and Chris Hopson is chief executive of NHS Providers.
The Children's Commissioner for England says the number of children being sexually abused is much higher than previously thought, estimating only one in eight comes to the attention of the authorities. Speaking on the programme is Chief Constable Simon Bailey, the National Police Chiefs' Council Lead on Child Protection, and Sue Crocombe, who was a victim of sexual abuse by a relative in her childhood.
Simon Armitage will deliver his inaugural lecture as Oxford University’s Professor of Poetry this afternoon. Mr Armitage is speaking live on the programme.
What is it like explaining the attacks in Paris to a child or young teenager? Our reporter Sima Kotecha has been to Elizabeth Garrett Anderson girl's school in North London.
The former Labour Defence Secretary, Des Browne, has warned that the Trident nuclear weapons system might be obsolete. Speaking on the programme is Laura Kuenssberg, the BBC’s Political Editor.
Two investigative journalists are among the five people who will be put on trial today by the Vatican for allegedly receiving leaked documents revealing corruption and waste in the Holy See. Speaking on the programme is Jack Valero, from Catholic Voices, a group which works to improve the Catholic Church’s representation in the media.
The former Cabinet minister Liam Byrne is today revealing he is the son of an alcoholic as he presses the government to work harder to help the estimated 2.6 million children - one in five - who now live with a "hazardous drinker". Liam Byrne is live in the studio.
Some say that the government - specifically the Business Department - has failed to articulate an industrial strategy. Our Industry correspondent John Moylan has been to the midlands near Coventry - one of our manufacturing heartlands.
From today, viewers will be able to ‘cast’ Channel 4 content from their Google Chromecast device to their TV sets. Speaking on the programme is Emily Reynolds, technology writer for Wired Magazine.
All subject to change.