It's an all-Welsh derby and a chance for Ryan Jones, Adam Jones and Alun Wyn Jones to take on fellow Grand Slammers Dan Lydiate, Toby Faletau and Luke Charteris. It's Shane Williams's last game at the Liberty Stadium, and it's a crucial match for the Ospreys in their quest for Pro12 glory.
For Scrum V, Sean Holley is in the analysis truck while Kingsley Jones is on the touchline with Phil Steele. Rob Jones joins Ross Harries in the studio and Stuart Davies teams up with Gareth Charles in commentary. On the red button you can get Rick O'Shea and Welsh language commentary.