Gary Lineker presents all the goals and highlights from the Barclay's Premier League.
Manchester United make the short journey to the Reebok Stadium, where Bolton upset them 1-0 last season to give Gary Megson his first win as the Wanderers' manager. Sir Alex Ferguson will be hoping his team can return to the form of the previous season, when they came away from Bolton with a 4-0 win courtesy of a Wayne Rooney hat-trick.
Chelsea aim to do the double over Stoke, while the Potters' fellow Premier League newcomers, Hull, will be hoping for a similar achievement as they face Arsenal, having enjoyed a shock win at the Emirates last September.
Sam Allardyce takes Blackburn Rovers to his former club, Newcastle United, who Rovers beat at St James's Park earlier this season. West Bromwich Albion are another side who have found victories hard to come by this season, and they play host to Middlesbrough, having won 1-0 at the Riverside.
Aston Villa are at Sunderland, while former Manchester United captain Steve Bruce takes his Wigan side to the home of Manchester City. The Latics beat City 2-1 at the JJB Stadium earlier this season, thanks to a controversial penalty earned by Wilson Palacios.