Manchester United and Arsenal are both through to the FA Cup fourth round after winning their replays.
Wayne Rooney scored the only goal in the 1-0 victory over West Ham. He missed a penalty later on.
The striker has been out with injury and was making his first appearance since Christmas.
Jack Wilshere helped Arsenal beat Swansea 1-0 with a late goal four minutes from time.
United will now face Fulham, while Arsenal will take on Brighton.
Chelsea 2-2 Southampton
In the Premier League, Chelsea threw away a lead to draw 2-2 with Southampton at Stamford Bridge.
Demba Ba and Eden Hazard both scored before the break to take the Blues 2-0 ahead.
But the Saints fought back, with second half goals from Rickie Lambert and Jason Puncheon.
It now leaves third-placed Chelsea 13 points behind top flight leaders Manchester United.