A Higher Media exam run by Inverness College UHI has been failed by all students for a second year in a row.
Roddy Henry, acting principal at Inverness College UHI, described the latest results as a "real shock".
The college said it had put in place additional support for the students as part of the redesign.
It is investigating the latest situation.
Most of those who sat the exam were aged between 16 and 18.
Scottish Qualifications Authority (SQA) said it provided "significant levels of ongoing support" to the college across all its subjects.
It said across Scotland the grade A to C attainment rate for Higher Media was 59.8% and the assessment "performed as intended".
Following last year's results, SQA also said the nationally-available 2016 Higher Media assessment had "performed as intended".
Inverness College UHI, which is part of the University of the Highlands and Islands, said it will not offer Higher Media in 2017/18.
It said this decision was taken before the latest results were known and as part of an ongoing review of courses the college offers.
Mr Henry said: "These results are a real shock and I am deeply disappointed that we are in this situation.
"The results are not in line with ongoing feedback and monitoring of the course, which was stringent this year given last year's results.
"They are by no means representative of the overall quality of provision at Inverness College UHI, where student success rates have improved year-on-year for the last four years.
"Overall, Higher results this year have been very good and in several cases well above the norm for Highers studied at colleges in Scotland."
He said overall pass rates in Maths was 71%, English 80%, Care 100%, Physics 83% and Biology 80%.
A spokesman for SQA said that following last year's fails it provided "extensive further support" to the college, including a visit from its principal assessor, to help the staff in their understanding of standards.
He added: "SQA has continued to work with Inverness College and in May the college indicated it would no longer be offering this course."
Have you been affected by the latest results from Inverness College UHI's Higher Media exam? Contactnewsonlinescotland@bbc.co.uk