Ayr's Gaiety Theatre, Dovecot Studios in Edinburgh and Wigtown Book Festival are among the arts organisations being given regular funding by Creative Scotland for the first time.
A total of 119 groups across the country were successful in their bids following an open application process.
But there were 145 failed bids, including ones from the Scottish Youth Theatre and Aberdeen's Sound Festival.
Creative Scotland allocated £100m as part of its Regular Funding programme.
Of the 119 successful organisations, most are artist-led, 20 are entirely new to long-term funding, 57 are moving from shorter-term funding arrangements and 42 already receive three-year funding.
The largest packages included £6.952m to the Edinburgh International Festival, £3.255m to Dundee Repertory Theatre and £3.2m to the Centre for the Moving Image.
Smaller beneficiaries included £550,000 to Hebrides Ensemble, £420,000 to Barrowland Ballet and £300,000 to Arbroath-based Hospitalfield Arts.
'Innovative and exciting'
Janet Archer, chief executive of Creative Scotland, said the successful groups represented "some of Scotland's most important, innovative and exciting cultural organisations, producing and presenting great work across craft, dance, film, literature, music, theatre and visual art.".
She added: "Importantly, these organisations will also provide significant support for thousands of individual artists and the broader workforce across Scotland's creative sector.
"Following a clear and robust decision-making process, the final portfolio includes a mix of organisational scale as well as reflecting Scotland's social and geographical diversity."
That diversity means the groups come from 21 different local authority areas, with more than three quarters of them operating beyond their base location.
Ms Archer added: "Arts and creativity can create a sense of wellbeing and transform the quality of life for everyone. Evidence shows they can play an important part in all of our lives, offering meaning and connection in a wealth of different ways.
"The organisations in this portfolio will make a significant contribution to this in Scotland."