Nottingham's city centre trams were disrupted after a fire which gutted a disused building and led to the evacuation of a nearby nightclub.
About 1,400 people were led to safety while crews tackled the blaze at the former Posh Spice restaurant in Goldsmith Street.
A large section of the road was closed on Thursday and trams were terminating at Forest Park and Ride.
Part of the severely damaged building was due be pulled down, say police.
No-one was hurt in the fire, the cause of which will be investigated once the area is made safe.
It broke out at about 0100 GMT, prompting the evacuation of the nearby Rescue Rooms nightclub as well as student accommodation.
The flames were extinguished, though firefighters were continuing to damp down the building, which was unsafe for crews to enter.
A front section of the building was expected to be demolished.
Supt Ian Howick, of Nottinghamshire Police, said: "The fire is well under control, however the structure of the building is now our major concern.
"Cordons and traffic diversions will remain in place while we continue to assess the building and carry out any demolition work deemed necessary.
"Our primary concern is to protect the public, make the area safe and protect the scene. We aim to get the roads and tram network open as soon as we can."
Extra buses were provided at Forest Park and Ride to transport people into the city centre.