The tallest residential building in the UK is set to be built after the Mayor of London decided not to oppose it.
The 68-storey South Quay Plaza, on the Isle of Dogs in east London, will reach a height of 722ft (220m).
The development will provide 888 residential units, 188 of which will be classed as affordable.
Plans were approved by Tower Hamlets Council in November and building work can begin, after the mayor said he would not call the plan in.
The project, on Marsh Wall near Canary Wharf, also includes a smaller 36-storey tower. Three existing commercial buildings will be demolished.
Changes from the original planning application, submitted by Berkeley Homes, include a reduction in the height of the main building from 73 storeys and the introduction of an affordable crèche in the smaller building.
A new north-south pedestrian route along the west of the site has also been added to plans.
Construction, which is expected to take five years, is due to start next January.
In a statement, Tower Hamlets Council said: "This will deliver new homes to our borough - 188 of which will be affordable - and will be a big part of our plans to transform the South Quay area into a thriving dockside neighbourhood."
The Isle of Dogs Neighbourhood Planning Forum said it was disappointed by the decision as it was concerned about the density of the development, especially in regards to transport capacity and the amount of space for children who would be living in the tower.
Forum secretary Andrew Wood, who is also a Conservative councillor for Canary Wharf, said: "Our main concern is that there is a completely inadequate play space for children and it is on an island, there are only two ways off the Isle of Dogs. What we want is a proper strategy for the area."